Jules Stein Eye Institute, UCLA is a medical group practice. Schwartz is also principal investigator in each of ACT's two Phase I/II clinical trials for Stargardt's macular dystrophy and dry age-related macular degeneration using RPE cells derived from stem cells.ĪCT said the trial will consist of 12 patients with cohorts of three patients receiving ascending dosages, and patients will be studied for one year. Steven Schwartz, MD Ophthalmology 31 Ratings Insurance Check Search for your. Steven Schwartz, professor of ophthalmology at the David Geffen School of Medicine at UCLA and retina division chief at UCLA's Jules Stein Eye Institute. Jules Stein Eye Institute 100 Stein Plaza, UCLA Box 957000 Los Angeles, CA 900957000 (310) 206-6035 The Foundation Fighting Blindness continued. In a statement, ACT said the primary focus of the Phase I and II study will be to evaluate the safety of the cells in patients who have severe myopic macular degeneration, or myopia, commonly known as nearsightedness. Jules Stein Eye Institute T oday, scientific progress is moving with unprecedented speed. English Deutsch Français Español Português Italiano Român Nederlands Latina Dansk Svenska Norsk Magyar Bahasa Indonesia Türkçe Suomi Latvian Lithuanian esk. Attention Your ePaper is waiting for publication By publishing your document, the content will be optimally indexed by Google via AI and sorted into the right category for over 500 million ePaper readers on YUMPU. English Deutsch Français Español Português Italiano Român Nederlands Latina Dansk Svenska Norsk Magyar Bahasa Indonesia Türkçe Suomi Latvian Lithuanian esk. Food and Drug Administration approval to perform clinical trials using ACT's retinal pigment epithelial (RPC) cells, which are derived from human embryonic stem cells, to treat nearsightedness. Annual Report 20102011 - Jules Stein Eye Institute. Looking Ahead: - Jules Stein Eye Institute. said its clinical partner, the University of California – Los Angeles (UCLA), has received U.S. Embryonic stem cells, taken from days-old human embryos, are especially pliable.Marlborough-based Advanced Cell Technology Inc. He is affiliated with Ronald Reagan UCLA Medical Center. He graduated from Keck Sch Of Med Of The Usc in 1988. Stem cells are the body’s master cells, the source of all other cells. Steven Schwartz, MD is an ophthalmology specialist in Los Angeles, CA and has over 34 years of experience in the medical field. In October, Geron Corp GERN.O enrolled the first patient in the first approved study of human embryonic stem cells, to treat people whose spinal cords have been crushed. ![]() The number of cases is expected to double over the next 20 years as the population ages, he noted. ![]() Steven Schwartz, who is leading the studies. “We hope that these cells will, in the future, provide a treatment not only for these two untreatable diseases - Stargardt’s disease and macular degeneration - but for patients suffering from a range other debilitating eye diseases.”Īge-related macular degeneration, or AMD, is a slowly progressing disease that first blurs vision and later causes a big black hole in the field of sight.ĭry AMD is the most common form of macular degeneration and the leading cause of blindness in the developed world, said UCLA’s Dr. Schwartz is affiliated with Ronald Reagan UCLA Medical Center. “After a decade of extensive research and preclinical studies, it is very satisfying to finally be moving into the clinic,” Lanza said in a statement. He works in Los Angeles, CA and 1 other location and specializes in Ophthalmology.
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Patients presenting within 24 hours of suspected NSTE-ACS – defined by ECG changes or elevated cardiac biomarkers – were randomized to receive aspirin plus a loading dose of 300 mg clopidogrel, and then 75 mg daily thereafter, compared to control receiving just aspirin. The CURE trial established the benefit of clopidogrel, with aspirin, given immediately on patient presentation with ACS (33). One of these subsets was patients with unstable angina.Ģ014 AHA Guidelines recommend giving 162 to 325 mg non-enteric coated aspirin, chewed, to all patients with suspected ACS (11). They found that aspirin at initial presentation, and then low dose daily, reduced serious vascular events in every subset of patients. In 2002, the Antithrombotic Trialists Group performed a meta-analysis of aspirin use in various cardiovascular disorders including acute stroke and acute MI (32). ( JM note: This topic might need its own deep dive at some point.) Aspirin The studies in this review used IV nitrates, primarily IV nitroglycerin.Ģ014 AHA guidelines recommend sublingual nitroglycerin to be administered to all patients with chest pain concerning for ACS, followed by IV nitroglycerin if the pain is refractory to sublingual medication (11). NitroglycerinĪ 2009 Cochrane Review concluded that nitrates reduce short-term mortality in patients with ACS (31). Of note, unstable angina is often grouped with NSTEMI and called NSTE-ACS. The following is a brief, up to date review of the literature on treating unstable angina. Should we be sending unstable angina to obs? What is the appropriate treatment of unstable angina?īy definition, patients with unstable angina are patients with ACS, and they should presumably be treated aggressively for ACS. Add a negative troponin and that seems like the patients who we would typically see in an observation unit. They used their own clinical algorithm to determine low risk, which they defined as 1 mm and 0.5 mm) or TWI (>3 mm) in at least 2 contiguous leads OR in a patient with known CAD (as diagnosed by angiography or prior MI) (29, 30).Īs you can see from this definition, a patient with chest pain, known CAD, and no ECG changes could technically have UA. In 1991, ED doctors at Brigham and Women’s Hospital published a study describing a “coronary observation unit” in which patients with low risk chest pain were monitored in an ED observation unit to rule out MI rather than being admitted to the hospital (9). Yet still, these patients were being admitted to the CCU for this observation period. It was determined that 12-24 hours was an acceptable observation period for ruling out MI (7, 8). Researchers developed decision aids to help identify low risk patients in the ED (5, 6), and ran studies to find the shortest amount of time in which MI could be ruled out. Admission of these “rule out MI” patients to an intensive care unit was costly, leading hospitals to seek ways of distinguishing the low risk patients earlier. Over half the patients admitted to the CCU with acute chest pain were eventually “ruled out” for myocardial infarction (4). ![]() However, the majority were low risk patients admitted simply to monitor for the development of acute MI with serial ECGs and cardiac enzyme measurement (CK-MB at that time). Some of these patients had acute MI and were treated accordingly. Up until the late 1980s, most patients presenting to the emergency department (ED) with acute chest pain were simply admitted to a coronary care unit (CCU) (3). Chest pain is the second most common reason for emergency department visits in the United States, and coronary artery disease is the leading cause of death (1,2). Part 1: A History of Observation for Chest PainĪccurate and expeditious diagnosis of acute myocardial infarction (MI) is one of the key charges of emergency departments and emergency providers. When not in the hospital he can be found surfing out on Rockaway Beach. Charles is a PGY-4 EM resident at Kings County Hospital/SUNY Downstate Medical Center with an academic interest in evidence-based medicine. ![]() Alejandro Mora has updated the log for Elegoo Mars 3 "Pro".Curtis Soldano has added a new log for Everything but the kitchen sink cyberdeck.CYUL liked PERSEUS-8 homemade 6502 computer.CYUL liked PERSEUS-9 homemade mobile 6502 computer.FulanoDetail has updated the log for DIY Mech/Exoskeleton suit.Peabody1929 liked DOOM on the Raspberry Pico and LCD screen.NiHaoMike on Canadian Engineers? They Have A Ring About Them.Miles Archer on Pedal Car Vs Ministry Of Transport.David on Arbitrary Waveforms On The Cheap.William Hostman on CP/M Is Now Freer Than It Was.Thomas Apostolidis on Flipping A Coin 10,000 Times With A Dedicated Machine.paulvdh on Inside A Cordless Soldering Station.Tomsz on Retrotechtacular: Building The First Computers For Banking.rclark on Blackberry Pi Puts Desktop Linux In Your Pocket.Drone on Arbitrary Waveforms On The Cheap.The PIC processor uses so little power that this tester should run for around 800 hours on a CR2032 watch battery.Ĭanadian Engineers? They Have A Ring About Them 96 Comments In fact, even included a diode test, which emits a short beep if the leads are placed across a working diode. The 5 10 bit ADC in the PIC is plenty of resolution for this sort of tester. Who needs a whole multimeter when you’re just trying to check continuity on a few circuits? This continuity tester uses a PIC12LF1571 processor to find open and short circuits. used a Piezo element in a slightly more mundane way – as a buzzer. If you see him online, tell him to hurry up! We’re hoping to turn our parking lot into a giant electronic chess board!įinally, we have with Low Power Continuity Tester. Initial tests were promising, but we haven’t heard much from on this project. This kind of measurement requires a decent processor, so is using the ARM Cortex-M0 in NXP’s LPC1114FN28. By measuring the vibration time of arrival, it should be possible to determine where the surface was touched. Touches with the rectangle will create vibrations in the surface that are transmitted to the piezo sensors. used a trio of Piezo disks to make any flat surface touch sensitive. The three sensors are placed at 3 corners of a rectangle. is next with Low-Cost Touchscreen Anywhere. Carefully controlling the voltage applied to the quadrants allows to move his STM tip in X, Y, and Z. Incredibly, this microscope is able to create images at the atomic scale. cut his piezo disk electrode into quadrants. These disks are used as speakers and buzzers in everything from smoke detectors to greeting cards, so they’re common and cheap. achieves that by using a normal piezo disk. The key to an instrument like this is precise movement. ![]() Inspired by a project from, created his own Scanning Tunneling Microscope (STM). Next up is with Scanning Tunneling Microscope. The ATmega328 running the strumpad then passes the velocity and note-on MIDI messages on to a synth. A piezo disc hiding below the circuit board detects how hard the notes have been strummed or tapped. Touching the strips determines which notes will be played. When the strumpad is strummed, six copper strips act as capacitive sensors. A music keyboard acts as the guitar fretboard here – keys can be pressed to choose notes, but no sound is generated. Strumpad lets you play a MIDI instrument by strumming, just like a guitar. This week’s Hacklet is all about some of the best projects utilizing the piezoelectric effect on Hackaday.io! The piezoelectric effect is used quite a bit in electronics, so it’s no surprise that plenty of hacker projects explore this physical phenomena. Only certain materials like crystals, some ceramics, and bone have piezoelectric properties. This doesn’t work for everything, though. The inverse is also true: Apply a voltage to a material, and it changes shape. The piezoelectric effect is simple in its rules: Apply mechanical stress to a material and you generate an electric charge. Don’t forget to request your sample kit as well. ![]() Remember, all quotes are free, so contact us today. Visit our website, or give us a call, for more information regarding the DuraShell®. If you prefer a custom sized sheet, we can accommodate you! 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Mendocino Redwood privacy framed lattice has a timeless, elegant quality and may be used in a number of ways to add charm to your backyard. When you have the framed lattice panel in the desired location, screw through the channel into railing and support post. We suggest framing the lattice sheet with channel first and then placing the panel between the rails and post. Simply frame the lattice sheet with the channel. Or you can use a u-channel to secure the lattice piece along the rail and post. This means the rail and post come with a “groove” in rails to accommodate the lattice sheet. One is you can use slotted rails and post. If you decide to extend the length or wrap the fence around an area, you have a couple of options. ![]() Options for Connecting Vinyl Lattice on a Fence Have you thought about using vinyl lattice?ĭepending on where you’re adding the vinyl lattice to the fence, the way you connect it can be different. Are you thinking about extending your vinyl fence? 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![]() The duration to carry out the test for.Targeting business customers, AIDA64 Business is a comprehensive IT. The screen mode and resolution, including windowed and fullscreen modes. AIDA64 is a system information, diagnostics and benchmarking solution for Windows PC.The number of objects displayed in the test. ![]() Select which Direct X version test to run.Many of the rendering options for the scene can be selected by the user. A scene with more objects, more textures and more DirectX features implemented may well look more impressive, but will more than likely result in a reduction in frame rate With DirectX 10, 11 and 12 tests being available if you are using a compatible video card and required version of Windows.Īpart from individual graphics card speeds and abilities, the test illustrates a single video card's drop in performance as the rendered scene becomes more complex. As such, PerformanceTest requires DirectX version 9 or above. It renders a number of scenes to the screen in windowed or full screen mode. The Advanced 3D Graphics Test has been designed to benchmark the how well your video card performs when using the most common features of DirectX. DirectX provides support for two-dimensional (2-D) and three-dimensional (3-D) graphics, sound effects, music, input devices, and networked applications such as multiplayer games. Microsoft provides a set of Application Programming Interfaces (APIs) called DirectX, which allow developers to create games and other high-performance multimedia applications. 3D Graphics technology has come on in leaps and bounds over the last few years and these tests can help measure how fast 3D images can be created and displayed. Included in PerformanceTest is the Advanced 3D graphics test which allows users to change the tailor the settings of the 3D tests to create one to suit their testing needs. ![]() Although long past its heyday, Iceberg still sells online to a new generation of fans. By the end of the 2010s, there were Iceberg boutiques worldwide, including Paris, Amsterdam, Dubai, Russia, and Kuwait, among others. The hip-hop community also took to Iceberg, giving Iceberg a kind of credibility other labels like Kangol and Under Armour already enjoyed. Iceberg hired newly minted stars to endorse the full-fledged lifestyle brand, like Paris Hilton and Pamela Anderson. Vintage ICEBERG History Turtleneck Sweater ad vertisement by MixandMatchPopUp Ad vertisement from shop MixandMatchPopUp MixandMatchPopUp From shop MixandMatchPopUp. The kidswear line called "Iceberg Junior" launched in 2002. Perfumes like "Fluid," "Effusion," and "Light Fluid" were released in quick succession throughout the early 2000s. ICEBERG SNOOPY WOODSTOCK SWEATER KNIT SZ L 1992 VINTAGE. ViNTaGe iCebeRG HiSToRY AnDy CaPP SWeaTer. Vtg RARE ICEBERG History Pepe LePew Sweater Mens XXL Gray Italy Made Pullover LS. ICEBERG HISTORY SWEATER Vintage Disney Goofy Full Zip Knit Sweater Large. In 2000, Paolo Gerani was appointed creative director of Iceberg, who brought fresh ideas to the table. RARE Vintage Iceberg History Goofy Sweater Black Medium Knit Short Sleeve. Four years later, the company launched its denim collection, "Iceberg Jeans." Two years later, after an eyewear collection premiered in 1996, the company held its first fashion show exhibiting a men's spring/summer collection. In 1991, Iceberg opened an American boutique in New York City and followed it with its first venture into leatherwear the next year. By this time, the Iceberg look was epitomized by rolled-up jeans, color-blocking, oversized shirts, and ubiquitous cartoon graphics. The brand's sales peaked in the 1990s as famous names garnered attention as spokespeople, including Isabella Rossellini, Sophia Coppola, Naomi Campbell, and Farrah Fawcett. It followed with a successful first fragrance, "Iceberg Femme," that spawned a sequel, "Homme," a year later. In 1989, Iceberg opened its first boutique and showroom in Milan. The brand's Mickey Mouse and Bugs Bunny sweaters and coats fit with the times but were timeless designs. ![]() ![]() Iceberg's products in the 1980s feature more of the same sportswear due to popular demand. By 1978, both knitwear collections often featured large-format images from cartoon characters and other pop-culture icons. In 1976, Iceberg launched its women's sportswear line. This sportswear stood out from other brands due to its embrace of details and influences from the world of art-including odes to Andy Warhol pop art-and its use of quality Italian fabrics. The two imagined creating a fashionable luxury sportswear line, beginning with men's knitwear. Founded in Italy in 1974, Iceberg was the brainchild of Silvano Gerani and Giuliana Marchini. |
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